I think of the concept "nightstand gun" as more of a concept than something to be taken literally. Point being, it doesn't have to be in the nightstand, you can put it somewhere within 5 feet that isn't the most apparent place for somebody to look, but that is still easy for you to access if you need to.
H&K Weapons -
9mm P7 PSP
.45 HK45 w/ Streamlight TLR-1
.45 USC/UMP Conversion w/ Eotech 512
Under Construction -
POF P-415 (AR15), Gen 3 Lower, Magpul UBR Stock, Enidine Hydraulic Buffer, Trijicon ACOG (model unchosen)
Everything Else -
.22 Browning Buckmark, Threaded Barrel, Barska Dot Optic
.22 Ruger 10/22, Threaded Barrel, Leupold Rifleman Optic
.22 AAC Pilot Suppressor (attaches to both above)
.22 Marlin Bolt-Action
.20-gauge Browning Pump