As others have stated you really shouldn't need to run 100oct. in a 10.5. Maybe fatten your tune a hair or pull a few degrees out up top. If its aluminum heads you definitely do not need it.
If its an original motor then it is probably not even 10.5 most motors were oversold.
Toulene will boost it, most oct. Boosters are toulene based or have it in there.
My guess is that over the years carbon build up has helped raise the compression some and it isn't far off from the state compression or even higher. I do have the motor at factory secs so I can back a few degrees of timing out of it but is that really going to take care of the pinging? Is Toulene going to have any negative affects on components? I have switched the rubber fuel line sections over to Gates Barrier, upgraded the fuel pump to accept corn gas and the original factory carb has been completely rebuilt to accept corn.