1)Run the takedown tension nut as tight as you can that allows you to still perform a takedown operation.
2)Find the ammo it likes.
3) Get a cantilever mount for the scope that attaches to the barrel.
4) Smooth out the inside of the receiver where the bolt rides.
5) if you want action tuned/trigger work down, etc. Randy at CT precision can fix you up. http://www.ct-precision.com/
I recommend you join the rimfire central forum and look around the 10-22 section and specifically the 10-22 takedown sub-forum.
There is a lot of good info there.