Regarding the 10mm program, the Bureau really started seriously looking into semi auto pistols right after the 1986 Miami shooting. The Bu wasn't really satisfied with the performance of the 9mm round and the .45cal was believed to be too much to handle for certain members for the Agent population. The S&W 1076 10mm pistol platform was developed and started hitting the field in the early 90's, however along with some production problems, the platform didn't sit well with Bu management and Agent alike and therefore only a few thousand (2500, comes to mind) were purchased from S&W.
Two great things came out of the 10mm program, however. The first being the extensive study into the field of wound/terminal ballistics. The exhaustive analysis of the projectile after it enters the body revealed just how much bullet caliber and shot placement plays on subject incapacitation. The results of these studies are still taught and used in training scenarios today. The second thing was the development of the widely used .40cal., which is really a 10mm short, developed by S&W. You see, the final 10mm round that the Bu used was downloaded to around 950 fps. This was done so that the entire agent population would be able to handle the weapon. S&W surmised that with less gun powder in the 10mm shell casing, the casing could be shorted and WALA, you have the S&W .40cal.
The Bu is currently issuing the Glock 22 and 23 (.40cal)
Basically, you can get a bit more penetration (you can load 10mm auto up to almost .357 mag levels, IIRC), but with modern hollowpoints, 9mm, .40, .45 and 10mm are all going to have almost identical performance on target.
Only the reduced power loads. Full power 10mm loads have more energy than the .40 S&W. (they call it .40 Short & Weak for a reason, ya know}The 10mm was effectively wiped out by it's shortened version, the .40 S&W. The history of the two cartridges is very interesting. Certainly the 10 mm has the potential for more power, but just how much power do you need?
The advantage of the .40/10mm over the .45 is that they are smaller diameter and make it easier to use a double-stack magazine. Where a 1911 holds 7 .45 rounds, a .40 pistol can hold 14 rounds.
Here's how it compares in ballistic gelatin:
Remington 180gr JHP
You can find the other calibers you're looking for on there, too. Basically, you can get a bit more penetration (you can load 10mm auto up to almost .357
mag levels, IIRC), but with modern hollowpoints, 9mm, .40, .45 and 10mm are all going to have almost identical performance on target. If I was looking for something to carry for cougar and black bear defense, a 10mm loaded hot with hard cast lead would fit the bill just fine. But for use against people, it's not very different than using an easier to handle caliber that takes up less space.
One thing we can all agree on is 10mm is cool. I do in fact need a Delta Elite 10mm, and I would totally conceal carry it.
Am I reading this correctly? A 9mm or a .40 cal have the same performance as the 10mm? As an example, Cor-Bon makes some of the hottest loads in most calibers (certainly the 9mm & .40), Double Taps are not significantly more powerful in those calibers:
Cor-Bon 9mm 115 grain +p: 1350 fps, 466 ft/pound
Cor-Bon .40 165 grain: 1150 fps, 485 ft/pound
Double Tap 10mm 165 grain: 1450 fps, 744 ft/pound
Identical performance? How is it that against four-legged predators, which are far stronger, tougher, and harder to kill than humans, the 10mm round is adequate, but when a much softer human target is concerned, the 9mm is just as effective? You lost me on that one.
I have nothing against 9mm or .40's. If that's what you can put on target effectively, God bless you. But after reading a LOT of cases on armed confrontation, abduction, home invasion, etc, many of which by drug-crazed assailants, it occurs to me that you'll get one very short amount of time to draw your weapon and get the first round off, hopefully two, and also hopefully near center of mass (but in a situation like that you may very well be happy hitting any part of the BG). If the lives of your family potentially hung on that one round, would you really prefer that round be a 9mm as opposed to a .45 or 10mm? The stats I cited, and many like it, are interesting and helpful, but real-world anecdotal evidence is a far better indicator, and every story I've read by LE, military, etc, who have been in gunfights, favor higher caliber and more powerful weapons.
I LOVE my Sig 226, and if I could handle it like the SEALs do, all the above is moot. But since I'm a once/twice a week range guy, I'm far better of with my G29, G30, or a 1911.
So let me be a little more precise. For defense against human aggressors, 10mm is equal in effectiveness (as well as such a thing can be measured) to 9mm, .40 and .45.
They are not "equal in effectiveness" within their own caliber due to the wide variety of loads & bullets that can be used, much less across other calibers.
ETA:
Here is a good thread, explaining why bigger is usually better:
Service Pistol Duty and Self-Defense Loads - M4Carbine.net Forums
"As you increase bullet size and mass from 9 mm/357 Sig, to .40 S&W, to .45 ACP, more tissue is crushed, resulting in a larger permanent cavity. In addition, the larger bullets often offer better performance through intermediate barriers."