300 Blk, everything stays the same except the bolt and barrel. It is an awesome round, especially if you plan on getting a can! If we weren't in an ammo crisis you would find it on shelves.
My opinion on .223/5.56 for deer is: Unless you are perfect with shot placement ( head or neck vertebrae ) you are going to lose a lot of deer. They may die, but miles away from where you shot them.
.223 is more than enough for a white tail depending on distance, bullet weight and placement.
I'd go with the 6.8 for hunting. Awesome little round.6.8spc or 300blk?
Actually, .224 bullet weights of 100 grains (and more, I'm sure) have been produced. I have several boxes of 100-grainers.Bullet weights go up to near 70 grains.
Not knocking 6.8, but.... if I already had a 556 and was going with a new caliber that requires different bolts and mags I'd take the 6.5G over the 6.8.
IMO, 6.8 is just not enough of an advantage over 300BLK to put up with all the duplication of parts and accessories. Everyone has their own preferences though.